Which of the following is NOT a live attenuated vaccine?

Prepare for the APhA Immunization Exam with flashcards and multiple choice questions. Detailed explanations and hints provided. Master the content for success!

In the context of vaccines, a live attenuated vaccine contains a version of the living microbe that has been weakened so it cannot cause disease in healthy individuals. The purpose of such vaccines is to stimulate a strong immune response that mimics natural infection without causing illness.

The influenza vaccine indicated as IIV (Inactivated Influenza Vaccine) is not a live attenuated vaccine; it contains killed virus particles. This means that it cannot replicate or cause the disease in the vaccinated individual, unlike live attenuated vaccines. The inactivated virus is used to elicit an immune response, providing protection against influenza without the risk of causing the disease itself.

On the other hand, varicella, typhoid (Ty21a), and yellow fever vaccines are all examples of live attenuated vaccines. Varicella (chickenpox) vaccine uses a weakened form of the varicella-zoster virus. The typhoid vaccine (Ty21a) uses a weakened strain of the bacterium Salmonella typhi, and the yellow fever vaccine contains a live attenuated strain of the yellow fever virus. Each of these vaccines works by inducing an immune response to the living organism that has been modified to prevent illness.

This distinction is crucial in understanding

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